Evolution of Bone Density, Bone Micro-architecture and Vascular Calcifications in Patients After Kidney Transplantation

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

The investigators project is based on: * Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); * The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; * Longitudinal evaluation of nephrological clinical parameters (glomerular filtration rate, number and type of rejections, immunosuppressive medications) as well as biological and urinary parameters of mineral metabolism (parathormone, sclerostin, bone alkaline phosphatase) depending on the type and severity of bone abnormalities; * The evaluation of these nephrological clinical parameters and of the biological parameters of mineral metabolism depending on the extent and evolution of vascular calcifications but also on bone morphology; * The study of possible relationships between bone mass and muscle mass (and functioning)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:

• At least 18 years old

• Recent kidney transplant patients (\<3 months)

• Medical history available

• Biological parameters of the past year available

Locations
Other Locations
Belgium
Centre Hospitalier Universitaire de Liège
RECRUITING
Liège
Contact Information
Primary
Antoine Bouquegneau
antoine.bouquegneau@gmail.com
+32473353321
Backup
Pierre Delanaye
pierre_delanaye@yahoo.fr
Time Frame
Start Date: 2020-09-01
Estimated Completion Date: 2026-12-13
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: University of Liege

This content was sourced from clinicaltrials.gov