Screening for Dysplasia in Longstanding Idiopathic Achalasia: a Prospective Study
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Patient with achalasia have a 10-50 fold increased risk to develop esophageal squamous cell carcinoma (ESCC). Early diagnosis of ESCC is essential, and detection of an earlier dysplastic stage is preferred. Endoscopic detection is however difficult and often delayed. Chromoendoscopy with Lugol dye increases detection rates dysplasia and ESCC to 91-100%. The aim of this study was therefore to evaluate a screening program using chromoendoscopy with Lugol to detect dysplasia in patients with idiopathic achalasia. A second objective is to study the relationship between foodstasis and the development op dysplasia
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• longstanding achalasia (\> 15y)
• \> 18y old
• informed consent
Locations
Other Locations
Belgium
UZleuven
RECRUITING
Leuven
Contact Information
Primary
an moonen, MD
an.moonen@med.kuleuven.be
Time Frame
Start Date: 2013-10
Estimated Completion Date: 2025-12
Participants
Target number of participants: 80
Treatments
Experimental: longstanding achalasia
Related Therapeutic Areas
Sponsors
Leads: KU Leuven