The Influence Of Bupivacaine Temperature On Subtenon Block Characteristics: A Prospective, Randomized, Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Sub-Tenon's anesthesia is now widely regarded as a preferred local anesthetic method for cataract surgery. Various techniques have been explored to prolong the duration, shorten onset time and improve the efficacy of local anesthetic nerve blocks with varying degrees of success. Warming local anesthetic may speed up its onset and prolong its effect by lowering its pKa.The aim of this study is to evaluate the effect of warming bupivacaine on the characteristics of a sub-Tenon's block in patients undergoing cataract surgery. It is hypothesized that warming bupivacaine 0.5% to 37°C will improve the characteristics of sub-Tenon's block. It will prolong the duration of sensory and motor block and accelerate the time onset time of sensory and motor block.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• American Society of Anesthesiology (ASA) I, II or III patients.

• Patients scheduled for elective unilateral cataract surgery.

Locations
Other Locations
Egypt
Mansoura University
RECRUITING
Al Mansurah
Contact Information
Primary
Amany H ELDeeb, MD
amanyhazem91@mans.edu.eg
+2-01008479726
Time Frame
Start Date: 2025-10-01
Estimated Completion Date: 2026-01
Participants
Target number of participants: 120
Treatments
Experimental: Operating room temperature bupivacaine
patients will receive local anesthetic (5ml containing 5mg bupivacaine) that will be on a sterile shelf in the operating room at 23°C. The empty syringes and needles will be also on the same shelf before their use.
Experimental: Warm bupivacaine
patients will receive local anesthetic (5ml containing 5mg bupivacaine) warmed to 37◦C for 20 minutes. The empty syringes and needles, in their packaging, will be held at the same temperature for at least 2 hours before initiating the block.
Related Therapeutic Areas
Sponsors
Leads: Mansoura University

This content was sourced from clinicaltrials.gov

Similar Clinical Trials