CDKL5 Deficiency Disorder Latest Advances

Find the Latest Research About CDKL5 Deficiency Disorder

Last Updated: 04/28/2026

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Found 306 publications

CDKL5 modulates the plasticity of excitatory synapses via liquid-liquid phase separation.

CDKL5 modulates the plasticity of excitatory synapses via liquid-liquid phase separation.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 18, 2026

Endocannabinoid Enhancement via MAGL Inhibition in CDKL5 Deficiency: Selective Cellular Benefits and Domain-Specific Functional Effects in Adult Cdkl5 KO Mice.

Endocannabinoid Enhancement via MAGL Inhibition in CDKL5 Deficiency: Selective Cellular Benefits and Domain-Specific Functional Effects in Adult Cdkl5 KO Mice.

Journal: International journal of molecular sciences
Published: February 11, 2026

Dynamics of CDKL5 phosphorylation and its regulatory mechanisms in cultured cells.

Dynamics of CDKL5 phosphorylation and its regulatory mechanisms in cultured cells.

Journal: Journal of biochemistry
Published: January 07, 2026

Loss of cyclin-dependent kinase-like 5 results in susceptibility to audiogenic seizures in mice.

Loss of cyclin-dependent kinase-like 5 results in susceptibility to audiogenic seizures in mice.

Journal: Epilepsia open
Published: December 03, 2025

A cross-correction gene therapy approach for CDKL5 deficiency disorder improves the pathological phenotype of CDD patient-derived cortical organoids.

A cross-correction gene therapy approach for CDKL5 deficiency disorder improves the pathological phenotype of CDD patient-derived cortical organoids.

Journal: Frontiers in bioengineering and biotechnology
Published: November 12, 2025

Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open-label prospective study.

Highly purified cannabidiol (CBD) in CDKL5 deficiency disorder (CDD): Open-label prospective study.

Journal: Epilepsia open
Published: November 08, 2025

Comments on: "Development and Validation of the Communication and Interaction Disorder-Observation Report (CID-OR) in CDKL5 Deficiency Disorder".

Comments on: "Development and Validation of the Communication and Interaction Disorder-Observation Report (CID-OR) in CDKL5 Deficiency Disorder".

Journal: Journal of child neurology
Published: October 25, 2025

Altered Short Non-Coding RNA Landscape in the Hippocampus of a Mouse Model of CDKL5 Deficiency Disorder.

Altered Short Non-Coding RNA Landscape in the Hippocampus of a Mouse Model of CDKL5 Deficiency Disorder.

Journal: Biomolecules
Published: September 23, 2025

Content Validation of the Communication Inventory Disability-Observer Reported (CID-OR).

Content Validation of the Communication Inventory Disability-Observer Reported (CID-OR).

Journal: Journal of child neurology
Published: September 03, 2025

CDKL5 Deficiency Disorder: Revealing the Molecular Mechanism of Pathogenic Variants.

CDKL5 Deficiency Disorder: Revealing the Molecular Mechanism of Pathogenic Variants.

Journal: International journal of molecular sciences
Published: August 15, 2025

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study.

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study.

Journal: Epilepsia
Published: August 11, 2025

An open-source pipeline for calcium imaging and all-optical physiology in human stem cell-derived neurons.

An open-source pipeline for calcium imaging and all-optical physiology in human stem cell-derived neurons.

Journal: bioRxiv : the preprint server for biology
Published: August 08, 2025
Showing 1-12 of 306

Last Updated: 04/28/2026