Validation of Breathing Event Detection of the Philips Respironics Sleep Therapy System REMstar Auto A-Flex Compared to Clinical Polysomnography

Status: Completed
Location: See all (3) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to demonstrate diagnostic agreement and determine the accuracy of the continuous positive airway pressure (CPAP) device compared to simultaneous, attended clinical polysomnography (PSG) in identifying breathing events in participants previously diagnosed with complex sleep apnea (CompSAS), complex sleep apnea with Cheyne-Stokes respiration (CSR), or obstructive sleep apnea (OSA).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 80
Healthy Volunteers: f
View:

• Males and females, ages 21-80.

• Able and willing to provide written informed consent.

• Diagnosis of complex sleep apnea (CompSAS) or Obstructive Sleep Apnea (OSA) within one year of study participation.

• For participants with CompSAS: (a) Diagnostic PSG with an Apnea-Hyopnea Index (AHI) greater than or equal to 10 events/hour and central apnea index (CAI) greater than or equal to 5 events/hour of sleep or (b) PAP titration with a CAI greater than or equal to 5 events/hour of sleep.

• For participants with OSA, a diagnostic PSG with an AHI greater than or equal to 15 events/hour of sleep.

• Must have had a CPAP titration such that the necessary PAP level to treat the sleep disordered breathing is known.

• Agreement to undergo a full-night, in-laboratory PSG on CPAP device.

Locations
United States
Colorado
National Jewish Health
Denver
Florida
University of Florida - Shands Sleep Disorders Center
Gainesville
Michigan
Sleep Health
Portage
Time Frame
Start Date: 2010-09
Completion Date: 2013-09
Participants
Target number of participants: 45
Treatments
Experimental: REMstar Auto with A-Flex
Manipulation of positive airway pressure (PAP) will occur throughout the night to induce breaking events. PAP will be set to the participant's prescribed pressure, increased until breathing events are induced, and then returned to the prescribed pressure. This cyclic pattern will continue throughout the night. Events will be measured with REMstar Auto with A-Flex.
Other: Manually Scored Polysomnography (PSG)
Manipulation of positive airway pressure (PAP) will occur throughout the night to induce breaking events. PAP will be set to the participant's prescribed pressure, increased until breathing events are induced, and then returned to the prescribed pressure. This cyclic pattern will continue throughout the night. Events will be Manually Scored Polysomnography (PSG).
Sponsors
Leads: Philips Respironics

This content was sourced from clinicaltrials.gov