Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Registry Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The aim of this study is to determine the clinical spectrum and natural progression of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) and related disorders in a prospective multicenter study, to assess the clinical, genetic and epigenetic features of patients with CADASIL , to optimize clinical management.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: t
View:
• Sign informed consent.
• Age\>18
• Clinical diagnosis of patients with CADASIL,and confirmed by genetic test or skin biopsy
• Asymptomatic NOTCH3 mutation carriers
• Relatives of CADASIL patients or carriers
• Unrelated healthy controls
Locations
Other Locations
China
Department of Neurology , First Affiliated Hospital Fujian Medical University
RECRUITING
Fuzhou
Contact Information
Primary
Lin Yi, PhD
caibin929@163.com
13615039153
Backup
Cai Bin, PhD
caibin929@163.com
13338413842
Time Frame
Start Date: 2020-03-09
Estimated Completion Date: 2049-03-09
Participants
Target number of participants: 1000
Treatments
CADASIL patients
Asymptomatic carriers of CADASIL
Relatives of CADASIL patients and carriers
Unrelated healthy controls
Related Therapeutic Areas
Sponsors
Leads: Bin Cai