Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury
Acute intermittent hypoxia (AIH) involves 1-2min of breathing low oxygen air to stimulate neuroplasticity. Animal and human studies show that AIH improves motor function after neural injury, particularly when paired with task-specific training. Using a double blind cross-over study we will test whether AIH and task-specific airway protection training improves airway protection more than training alone in individuals with chronic mild-moderate traumatic brain injury (TBI).
• Adults aged 21-80 years
• A mild to moderate traumatic brain injury (TBI) confirmed by medical records
• A Glasgow Coma Scale score between 9-15
• Able to consent independently
• Women of child-bearing age must be comfortable confirming a negative pregnancy prior to participating in the study