Cerebral Palsy Clinical Trials

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Early Detection & Intervention of Cerebral Palsy in Ireland

Status: Recruiting
Location: See all (5) locations...
Study Type: Observational
SUMMARY

Cerebral palsy (CP) is the most common lifelong physical disability. It is defined as a non-progressive disorder of movement originating from neural lesions in the perinatal period, and is associated with a wide range of common comorbidities in many individuals. These include problems speaking, hearing, seeing, thinking, feeding and controlling their bladder. People with CP often have additional challenges such as behavioural and emotional issues, pain, and poor sleep. Many of these challenges respond well to intervention in early childhood, as brain plasticity is at its greatest in the first 2 years of life. However, in most clinical settings, the age for diagnosis of CP is between 24 to 29 months, after this window of neurodevelopmental opportunity. This project will aim to improve the Early Detection of Cerebral Palsy in Ireland. This will be achieved by implementing an evidence-based approach to follow-up of High risk infants.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 9 months
Healthy Volunteers: f
View:

• Legal guardians must be able and willing to give written informed consent and to comply with the requirements of this study protocol.

• All infants considered high risk for cerebral palsy and neuro-developmental impairment will be eligible, specifically including:

‣ All preterm infants born ≤32 weeks Post Menstrual Age or ≤1500 gm birth weight

⁃ All encephalopathic infants

⁃ Neurological risk factors (e.g., injury/malformation on neuroimaging, persistently abnormal neurological exam)

Locations
Other Locations
Ireland
Cork University Maternity Hospital
RECRUITING
Cork
Coombe Women and Infants University Hospital
RECRUITING
Dublin
National Maternity Hospital
RECRUITING
Dublin
The Rotunda Hospital
RECRUITING
Dublin
University Maternity Hospital Limerick
NOT_YET_RECRUITING
Limerick
Contact Information
Primary
Brian H Walsh
brianhenry.walsh@ucc.ie
021 42020529
Backup
Teresa Berkery
t.berkery@ucc.ie
Time Frame
Start Date: 2023-07-01
Estimated Completion Date: 2028-06-30
Participants
Target number of participants: 1500
Related Therapeutic Areas
Sponsors
Collaborators: Cork University Maternity Hospital, Coombe Women and Infants University Hospital, National Maternity Hospital, Ireland, Cerebral Palsy Foundation, The Rotunda Hospital, University Maternity Hospital Limerick
Leads: University College Cork

This content was sourced from clinicaltrials.gov