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Bimanual Training Versus Unilateral Task Specific Training in Children With Spastic Hemiplegic Cerebral Palsy

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Cerebral palsy is one of the most common childhood neurological disorders and often results in weakness, poor coordination, and stiffness (spasticity) in one side of the body in children with spastic hemiplegic cerebral palsy. These difficulties can significantly affect a child's ability to perform daily activities such as dressing, eating, playing, and school-related tasks. Upper limb rehabilitation plays a crucial role in improving independence and quality of life in these children. Two commonly used rehabilitation approaches are bimanual training, which focuses on using both hands together during functional tasks, and unilateral task-specific training, which focuses intensively on improving the affected hand through repetitive, goal-directed activities. Although both approaches are widely practiced in pediatric neurorehabilitation, there is limited direct comparison of their effectiveness in reducing spasticity and improving functional independence among children with spastic hemiplegic cerebral palsy, particularly in the local population of Pakistan. This randomized controlled trial aims to compare the effectiveness of bimanual training versus unilateral task-specific training in children aged 5-12 years diagnosed with spastic hemiplegic cerebral palsy. A total of 46 participants will be randomly assigned to one of two intervention groups. Both groups will receive therapy three times per week for eight weeks. Spasticity will be measured using the Modified Ashworth Scale (MAS), and functional independence will be assessed using the Pediatric Evaluation of Disability Inventory (PEDI). Assessments will be conducted before and after the intervention period. The results of this study may help clinicians, caregivers, and rehabilitation centers determine which therapy approach is more effective in improving upper limb function and independence in children with spastic hemiplegic cerebral palsy. Participation in this study is voluntary, and children may withdraw at any time without affecting their standard care.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 15
Healthy Volunteers: f
View:

• Both male and female Children diagnosed with spastic hemiplegic cerebral palsy (confirmed by a pediatric neurologist or rehabilitation specialist).

• Age range: 5 to 12 years (suitable for both bimanual and unilateral task-specific training).

• Gross Motor Function Classification System (GMFCS) levels I to III (ambulatory with or without limitations).

• Modified Ashworth Scale score between 1 and 3 in the upper limb muscles (indicating mild to moderate spasticity).

• Minimum cognitive ability to follow simple instructions, verified using screening tools (e.g., MMSE adapted for children).

• Ability to sit unsupported for at least 30 seconds (to ensure safe participation in therapy).

Locations
Other Locations
Pakistan
University of Lahore Teaching Hospital, Lahore
RECRUITING
Lahore
Contact Information
Primary
Muhammad Hasnain Soomro, MSPTN
drhasnainsoomro@gmail.com
03158463003
Backup
Montiha Azeem, MSPTN
muntahaazeem9@gmail.com
03479717317
Time Frame
Start Date: 2026-03-01
Estimated Completion Date: 2026-05-02
Participants
Target number of participants: 46
Treatments
Experimental: group A Bimanual Training Group
Participants in this group will receive structured bimanual training designed to improve coordination, reduce spasticity, and enhance functional use of both upper limbs. The intervention will be delivered three sessions per week for 8 weeks, with each session lasting 60 minutes. Activities will include repetitive, goal-directed bilateral tasks such as buttoning shirts, folding clothes, opening containers, building with blocks, and bimanual play activities. Each session will be divided into three 20-minute activity blocks with 5-minute rest intervals to prevent fatigue. All sessions will be supervised by a certified pediatric physiotherapist trained in neurorehabilitation. In addition, participants will receive standardized baseline physiotherapy education at the start of the study.
Active_comparator: group B Unilateral Task-Specific Training Group
Participants in this group will receive unilateral task-specific training focused on intensive use of the affected upper limb to promote neuroplasticity and functional recovery. The intervention will be delivered three sessions per week for 8 weeks, with each session lasting 60 minutes. Activities will include grasp-and-release exercises, reaching, stacking, drawing, flipping cards, and manipulation of objects using the affected hand. The unaffected hand may be mildly restrained when necessary to encourage active use of the affected limb without causing frustration. Sessions will be structured into three 20-minute blocks with 5-minute rest intervals. Standardized baseline physiotherapy education will also be provided at the beginning of the study.
Related Therapeutic Areas
Sponsors
Leads: Montiha Azeem

This content was sourced from clinicaltrials.gov