Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The study aims to compare the feasibility and effectiveness of using an internal nasal splint- supported free graft versus a nasoseptal flap alone for endoscopic repair of bilateral CSF leaks. Research question: Does the use of an internal nasal splint to support a free graft during endoscopic repair of bilateral CSF leaks improve outcomes compared to the use of a nasoseptal flap alone?
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• 3- Patients with bilateral CSF leak and sever septal spur. 4- Patients with bilateral CSF leak and history of submucosal resection of nasal septum.
• 5- Patients with bilateral CSF leak and large septal perforation. 6- Patients with bilateral CSF Leak and septal granuloma.
Locations
Other Locations
Egypt
Kafrelsheikh Faculty of Medicine
RECRUITING
Kafr Elsheikh
Contact Information
Primary
Amr Maher Shady, resident
amrshady00@gmail.com
0473109517
Time Frame
Start Date: 2026-02-01
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 20
Treatments
Experimental: Nasoseptal Flap for Endoscopic Skull
• Group A: Free graft + Internal nasal splint~* Free graft material (e.g., fascia lata, fat, synthetic dural substitute) placed over the defect.~* Internal nasal splint applied to support the graft and maintain its position
Experimental: Evaluation of Internal Nasal Splint-Supported Free Graft in Endoscopic Skul
• Group B: Nasoseptal flap alone.~\- Standard nasoseptal flap technique used for skull base repair.
Related Therapeutic Areas
Sponsors
Leads: Kafrelsheikh University
Collaborators: Faculty of medicine kafr elshiekh university