Plasma Circulating Tumor HPVDNA and Transrenal HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Definitive Treatment
Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY
The purpose of this study is to determine if ctHPVDNA (circulating tumor HPV DNA) can be used as a non-invasive biomarker for identification and treatment monitoring of cervical cancer by characterizing correlation between plasma ctHPVDNA, urine transrenal HPVDNA (TrHPVDNA) levels and presence of cervical cancer at diagnosis and following definitive intent management.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• 18 years of age or older on day of signing informed consent
• New diagnosis of cervical cancer
• Subject is willing and able to comply with study procedures based on the judgement of the investigator or protocol designee
Locations
United States
North Carolina
Melissa Knutsen
RECRUITING
Chapel Hill
Other Locations
Malawi
Kamuzu Central Hospital
NOT_YET_RECRUITING
Lilongwe
Contact Information
Primary
Melissa E Knutsen
melissa_knutsen@med.unc.edu
919-445-4869
Time Frame
Start Date: 2024-05-03
Estimated Completion Date: 2027-01-15
Participants
Target number of participants: 30
Authors
Related Therapeutic Areas
Sponsors
Leads: UNC Lineberger Comprehensive Cancer Center