ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

The aim of this study is to look at whether an Artificial Intelligence (AI) based computer program can automate two components of the radiotherapy treatment pathway to a sufficient quality standard to enable its routine clinical use. The two components include the delineation (outlining) of anatomical areas that are at risk of tumour spread and at risk of radiation damage, and the definition of the position, size and shape of the radiation beams. The AI-based computer programs have been developed to perform tasks that would normally require direct human involvement by oncologists and medical physicists. Proposed advantages include improved treatment accuracy, as well as a reduction in the time (from weeks to minutes) and human resources needed to deliver radiotherapy, which this study will test.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Consecutive patients with histologically confirmed head and neck cancers of the oropharynx, larynx, hypopharynx and nasopharynx (Stage I-III) that have given consent for radical radiotherapy.

• Consecutive histologically confirmed primary cervical cancer patients (Stage IB-IIIB including pelvic node positive) that have given consent for radical radiotherapy.

• Consecutive histologically confirmed primary prostate cancer patients (T1-4N0M0) that have given consent for radical radiotherapy.

• Mental capacity to understand and consent to participate in the study.

• Patients aged ≥18years.

Locations
Other Locations
India
Tata Medical Centre
RECRUITING
Kolkata
Tata Memorial Hospital
RECRUITING
Mumbai
Jordan
King Hussein Cancer Center
RECRUITING
Amman
Malaysia
University of Malaya Medical Center
RECRUITING
Kuala Lumpur
South Africa
Groote Schuur Hospital
RECRUITING
Cape Town
Tygerberg Hospital
NOT_YET_RECRUITING
Stellenbosch
Contact Information
Primary
ARCHERY Trial Manager
mrcctu.archery@ucl.ac.uk
+442076704637
Time Frame
Start Date: 2023-12-07
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 990
Related Therapeutic Areas
Sponsors
Collaborators: Rising Tide Foundation, University Ghent, Medical Research Council, Tata Memorial Centre, Mount Vernon Cancer Centre at Mount Vernon Hospital, Tata Memorial Hospital, University of Malaya, M.D. Anderson Cancer Center, King Hussein Cancer Center, University of Stellenbosch, National Institutes of Health (NIH), National Cancer Institute (NCI), University of Cape Town
Leads: University College, London

This content was sourced from clinicaltrials.gov