The Prognostic Value of Conization and Negative HPV Typing After Conization Prior to Surgical Intervention in Adenocarcinoma in Situ and Early Stage Cervical Cancer
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
In women with cervical cancer -Squamous cell carcinoma, Adeno carcinoma, Adeno-squamous carcinoma or AIS we want to examine prospectively: 1. Examine if negative HR-HPV after conization to the HR-HPV the women had before conization has a high prognostic value for no residual tumor in the final pathology. 2. To examine if conization in women with cervical tumor up to Stage I B 2 (FIGO 2018) is corelated with better prognosis.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:
• Age Range: 18-85 years old Cervical cancer stage I B 2(Tumor up to 4 cm FIGO 2018) AIS HPV types before and after conization
Locations
Other Locations
Israel
Rambam Health Care Center
RECRUITING
Haifa
Contact Information
Primary
Yoav Siegler, MD
yoav.siegler@gmail.com
+972528263054
Time Frame
Start Date: 2023-07-26
Estimated Completion Date: 2028-07-01
Participants
Target number of participants: 200
Treatments
Post Conization HR HPV positive
Women with a Post Conization cervical test positive for HR HPV
Post Conization HR HPV negative
Women with a Post Conization cervical test negative for HR HPV
No Conization HR HPV positive
Women who did not go through Conization prior to surgery and had a cervical test positive for HR HPV
No Conization HR HPV negative
Women who did not go through Conization prior to surgery and had a cervical test negative for HR HPV
Related Therapeutic Areas
Sponsors
Leads: Rambam Health Care Campus