• 1\. The Patients (or legally authorized representative) Patients (or legally authorized representative) must have the ability to understand the requirements of the study, have provided written informed consent as evidenced by signature on an informed consent form (ICF) approved by an Institutional Review Board/Independent Ethics Committee (IRB/IEC) ,must have the ability to understand the requirements of the study);

• 2\. The patient must be 18 to 70 years of age at the time of consent;

• 3\. Must have a confirmed diagnosis of malignancy of their receptive histologies or cytology: unresectable recurrent or metastatic cervical carcinomas and previously received≥ 1 prior systemic therapy;

• 4\. Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1;

• 5\. Expected survival time of ≥ 12 weeks;

• 6\. Adequate normal organ and marrow function;

• 7\. Before tumor resection, the confirmatory imaging of disease progress since last treatment should be documented.

• 8.Patients must have measurable disease measured by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria (in addition to the resected lesion).