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Improving Cervical Cancer Screening Coverage Among Underscreened Women Aged 50 to 74 in Switzerland Using HPV Self-sampling Strategies: A Randomized Study - Breast Cancer-Related Approach for Increasing Cervical Cancer Screening

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The primary objective of this clinical trial is to assess cervical cancer screening participation among under-screened women invited through organized breast cancer screening programs in Switzerland. This randomized trial will compare three arms: 1. Intervention group 1: Sensitization to Cervical Cancer (CC) screening Women will receive an awareness letter explaining the importance of cervical cancer screening, the Swiss recommendations and an invitation to schedule an appointment. 2. Intervention group 2: Home-based Human papillomavirus infection (HPV) self-sampling Women will receive a free-of-charge vaginal self-sampling kit for HPV infection 3. Observational control group Women selected in the control arm will only be recruited one year following the screening of those in the intervention arm (T0+1), as to not influence Cervical Cancer Screening (CCS) behavior during this period by being reminded of screening recommendations.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 50
Maximum Age: 74
Healthy Volunteers: t
View:

• Women receiving Breast Cancer Screening (BCS) invitation letters in the selected five cantons (Geneva, Bern (francophone), Jura, Neuchâtel, and Vaud)

• Aged 50 to 74 years old

• Not been screened for cervical cancer in the past three years

• Speaking one of the 6 languages of the study (French, German, Italian, and in English, Spanish, and Portuguese)

Locations
Other Locations
Switzerland
University Hospitals of Geneva
RECRUITING
Geneva
Contact Information
Primary
Jessica Di Vincenzo-Sormani, PhD
jessica.di-vincenzo-sormani@hesge.ch
+41 22 558 58 78
Backup
Patrick Petignat, MD
Time Frame
Start Date: 2025-10-07
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 4500
Treatments
Experimental: Intervention Group 1: Sensitization to Cervical Cancer (CC) screening
Women will receive an awareness letter explaining the importance of cervical cancer screening, the Swiss recommendations and an invitation to schedule an appointment.
Experimental: Intervention Group 2: Home-based HPV self-sampling
Women will receive a free-of-charge vaginal self-sampling kit for HPV infection.
Sponsors
Collaborators: University Hospital, Geneva
Leads: Jessica Di Vincenzo Sormani

This content was sourced from clinicaltrials.gov