Efficacy and Safety of Chinese Medicine in the Treatment of Chikungunya Fever: A Real-World Observational Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This study aims to evaluate the effectiveness and safety of Chinese Medicine-used alone or combined with Western medicine-in treating chikungunya fever, a mosquito-borne viral disease causing fever, rash, and severe joint pain. With recent outbreaks in China (including over 3,000 cases in Foshan, Guangdong) and no specific antiviral treatment available, Chinese medicine may offer a valuable therapeutic option based on its symptom-relief and syndrome-specific approach.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Meets the suspected or confirmed diagnostic criteria for chikungunya fever;
• Symptom onset ≤3 days before enrollment;
• Actual prescribed treatment aligns with the study's group assignment (TCM, Western medicine, or combined therapy)
• Signed informed consent form
Locations
Other Locations
China
Guangdong Province Hospital of Tradtional Chinese Medicine
RECRUITING
Guangzhou
Time Frame
Start Date: 2025-07-26
Estimated Completion Date: 2026-12-26
Participants
Target number of participants: 600
Treatments
Chinese Medicine Group
Intervention: Patients receive only TCM treatments, which may include herbal formulas (e.g., decoctions, granules) or acupuncture, tailored to their syndrome differentiation (e.g., heat-clearing, detoxifying, or dampness-resolving therapies).
Western Medicine Group
Intervention: Patients receive only standard Western medical care, which may include antipyretics (e.g., acetaminophen), NSAIDs for pain, and supportive treatments (e.g., hydration).
Integrated Therapy Group
Intervention: Patients receive both Chinese and Western treatments.
Related Therapeutic Areas
Sponsors
Leads: Guangzhou University of Traditional Chinese Medicine