Chronic Idiopathic Constipation (CIC) Clinical Trials

• Patients ≥18 to ≤80 years old at the Screening visit (Visit 1).

• Meet the Rome IV Diagnostic Criteria for functional constipation.

• Females of non-childbearing potential, or agree to the use of an acceptable means of contraception for up to 30 days following the last dose of study medication.

• Males must agree to use an appropriate method of barrier contraception or have documented surgical sterilization.

• Meets the entry criteria assessed during the Screening period.

• Ability to understand and provide input on the assessments in the eDiary.

• Provide written informed consent before the initiation of any study-specific procedures.

• Must agree to have daily access to eDiary via a computer, tablet or smart phone