Chronic Idiopathic Constipation Symptoms, Doctors, Treatments, Advances & More

Learn About Chronic Idiopathic Constipation

What is the definition of Chronic Idiopathic Constipation (CIC)?

Chronic idiopathic (of unknown cause) constipation is a persistent condition that mainly affects females and older adults and is characterized by infrequent, hard, and lumpy stools that are extremely difficult to pass. This creates a buildup of stool in the colon that causes extreme abdominal and pelvic pain. While the cause is unknown, chronic idiopathic constipation may be triggered by reduced fluid and fiber intake; the use of certain medications, such as antihistamines, antipsychotic medications, opioids, general anesthetics, and antiparkinsonian drugs; changes in the colon; rectocele (rectum bulging into vagina); rectal prolapse (rectum protrudes through the anus); or dyssynergic dysfunction (disorder of muscles and sphincters that control defecation).

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What are the symptoms of Chronic Idiopathic Constipation (CIC)?

Symptoms of chronic idiopathic constipation may include chronic constipation (fewer than three bowel movements a week) that persists for six months or more with hard stools; a feeling of incomplete bowel evacuation; a sensation of a blockage in the rectum or anus; straining upon defecation; abdominal pain and bloating; back pain; poor appetite; a general feeling of being unwell (malaise); and the necessity of using the hands to facilitate defecation.

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What are the current treatments for Chronic Idiopathic Constipation (CIC)?

Treatments for chronic idiopathic constipation include laxatives, such as milk of magnesia, lactulose, and polyethylene glycol (PEG); glycerin suppositories; enemas; stimulant laxatives, such as bisacodyl, glycerol, or sodium picosulfate; linaclotide; prucalopride; fiber laxatives, such as psyllium, calcium polycarbophil, inulin, and maltodextrin; prucalopride; velusetrag; lubiprostone; linaclotide; increased dietary fiber and water intake; probiotics; physical exercise; and biofeedback training.

Who are the top Chronic Idiopathic Constipation Local Doctors?

Dr. William D. Chey

Gastroenterology

Elite

Highly rated in

conditions

Gastroenterology

Michigan Medicine

University Hospital

1500 E Medical Center Dr,

Ann Arbor, MI

William Chey is a Gastroenterologist in Ann Arbor, Michigan. Chey has been practicing medicine for over 37 years and is rated as an Elite expert by MediFind in the treatment of Chronic Idiopathic Constipation (CIC). He is also highly rated in 34 other conditions, according to our data. His top areas of expertise are Irritable Bowel Syndrome, Chronic Idiopathic Constipation (CIC), Diarrhea, Endoscopy, and Colonoscopy. He is licensed to treat patients in Michigan. Chey is currently accepting new patients.

Marc A. Benninga

Elite

Highly rated in

conditions

Emma Children's Hospital

Amsterdam, NL

Marc Benninga practices in Amsterdam, Netherlands. Benninga is rated as an Elite expert by MediFind in the treatment of Chronic Idiopathic Constipation (CIC). He is also highly rated in 39 other conditions, according to our data. His top areas of expertise are Chronic Idiopathic Constipation (CIC), Gastroesophageal Reflux in Infants, Gastroesophageal Reflux Disease, Sacral Nerve Stimulation, and Ileostomy.

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Dr. Darren M. Brenner

Gastroenterology

Elite

Highly rated in

conditions

Gastroenterology

Northwestern Medicine

Northwestern Medical Group

676 N Saint Clair St,

Chicago, IL

Darren Brenner is a Gastroenterologist in Chicago, Illinois. Brenner has been practicing medicine for over 21 years and is rated as an Elite expert by MediFind in the treatment of Chronic Idiopathic Constipation (CIC). He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Chronic Idiopathic Constipation (CIC), Irritable Bowel Syndrome, Diarrhea, Colonoscopy, and Endoscopy. He is licensed to treat patients in Illinois. Brenner is currently accepting new patients.

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What are the latest Chronic Idiopathic Constipation Clinical Trials?

A Phase 3, Multicenter, Randomized, Double-blind, Parallel-group, Safety and Efficacy Study of Linaclotide Versus Placebo in Pediatric Subjects, Ages 2 to 5 Years, With Functional Constipation (FC) With a 24-week Open-label Treatment Extension

Enrollment Status: Not yet recruiting

Publish Date: December 15, 2022

Intervention Type: Drug

Study Phase: Phase 3

Summary: Functional constipation (FC) is a common healthcare problem in children of all ages, potentially due to genetic predisposition, inadequate fiber and fluid intake, and immobility. Currently, there are no pharmacological therapies approved for the treatment of FC. This study will assess adverse events and change in disease activity with linaclotide therapy in participants with FC. Linaclotide is an ...

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Phase 3, Multicenter, Randomized Study With 2 Different Doses of Prucalopride Administered to Male and Female Pediatric Subjects Aged 6 Months to 17 Years With Functional Constipation, Consisting of a 12-week Double-blind, Placebo-controlled Part (Part A) to Evaluate Efficacy and Safety Followed by a 36-week Double-blind Extension Part (Part B) to Document Long-term Safety up to Week 48

Enrollment Status: Recruiting

Publish Date: December 07, 2022

Intervention Type: Drug, Other

Study Phase: Phase 3

Summary: Functional constipation is a condition when it is very hard to pass a stool that is not due to any other health problem or to medicines being taken. This condition is more common in children and teenagers. This study has 2 parts: The main aim of the 1st part of the study is to learn if a medicine called prucalopride can improve bowel movements in children and teenagers with functional constipation...

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What are the Latest Advances for Chronic Idiopathic Constipation?