Assessment of T-cell Response and In-vitro Proof-of-concept of T-cell Engineering in Chronic End-stage Kidney Disease Patients.
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This is a comparative, prospective, non-interventional study to evaluate immune response in patients with chronic kidney disease. The primary objective is to define immunodeficiency (phenotype and function of T cells) in patients with end-stage kidney disease. The second objective is to provide an in-vitro proof-of-concept of T-cell engineering in the context of end-stage kidney disease. The study population was patients with chronic kidney disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Male or female ≥ 18 years
• Informed participants who did not object to participating in the study
Locations
Other Locations
France
Center Hospitalier Universitaire d'Orléans
RECRUITING
Orléans
Contact Information
Primary
Manon DEKEYSER, PhD
manon.dekeyser@chu-orleans.fr
+33238229870
Time Frame
Start Date: 2024-11-27
Estimated Completion Date: 2026-12
Participants
Target number of participants: 100
Treatments
n°1 (ESKD)
end-stage chronic kidney disease
n°2 (stage 3 CKD)
stage 3 chronic kidney disease
n°3 (healthy donors)
healthy donors
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Régional d'Orléans