Repletion of Ergothioneine in Patients With Kidney Failure
Status: Recruiting
Location: See location...
Intervention Type: Other, Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Dialysis removes potentially harmful chemicals from the blood but can also remove potentially valuable chemicals. One potentially valuable chemical called ergothioneine, which comes from the diet, is low in the blood of people receiving dialysis. For this research study, the investigators hope to learn how well a daily ergothioneine supplement will replenish the levels in the blood of people with kidney failure.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• kidney failure receiving hemodialysis or peritoneal dialysis
Locations
United States
California
Veterans Affairs Palo Alto
RECRUITING
Palo Alto
Contact Information
Primary
Tammy Sirich, MD
tsirich@stanford.edu
650-493-5000
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2030-12
Participants
Target number of participants: 28
Treatments
Experimental: Ergothioneine
Ergothioneine (range 5 mg to 25 mg) oral daily for up to 12 weeks
Placebo_comparator: Placebo
Matching placebo oral daily for up to 12 weeks
Related Therapeutic Areas
Sponsors
Leads: Stanford University