Chronic Kidney Disease Clinical Trials

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Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Fluid overload, which is when your body has too much fluid, is one of the reasons why people on home dialysis need to go to the hospital. Fluid overload (when body has too much fluid) commonly presents as trouble breathing and leg swelling. Traditionally, doctors check for this by asking patients if they have any symptoms like leg swelling or shortness of breath and by doing a physical exam which includes listening to the lungs or looking for swelling in legs. However, a newer, safe, and non-invasive method called point-of-care ultrasound (POCUS) has become very popular. However, we don't have a lot of research yet on how POCUS and LUS (lung ultrasound) specifically help home dialysis patients, including those on peritoneal dialysis or home hemodialysis. Peritoneal dialysis is a way to clean your blood by putting a special fluid into your belly through a small tube. The fluid uses the natural lining of your belly as a filter to remove waste and extra water. Home hemodialysis is a treatment where a machine acts like an artificial kidney to clean your blood. You get trained to do this yourself at home by connecting to the machine with a couple of needles, which cleans your blood of waste and extra fluid. POCUS, especially a (LUS), has been shown to be useful for dialysis patients in outpatient units. This study will compare different 3 different methods of detecting fluid overload: answering various survey questions, completing a physical exam, and a LUS. The study seeks to determine which of these methods is the best method to determine fluid overload. You were selected as a possible participant because you are over 18 years old, diagnosed with End-stage kidney disease, and have been receiving home dialysis for at least three months.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Age: Greater than 18 years.

• Diagnosis: End-stage kidney disease (ESKD).

• Treatment: Receiving home dialysis, either peritoneal dialysis (PD) or home hemodialysis (HHD).

• Duration of Home Dialysis: At least three months on home dialysis.

Locations
United States
Indiana
Davita Home Dialysis of Indianapolis
RECRUITING
Indianapolis
Contact Information
Primary
Nupur Gupta
nugupta@iu.edu
317-278-2868
Backup
Srinath Yadlapalli
syadlap@iu.edu
Time Frame
Start Date: 2026-01-09
Estimated Completion Date: 2026-06
Participants
Target number of participants: 90
Treatments
Only a single cohort/group
This study includes only one group all of whom get the same testing
Related Therapeutic Areas
Sponsors
Leads: Indiana University

This content was sourced from clinicaltrials.gov