Biological Investigation of Explanted Endobronchial Lung Valves Study - Investigation of the Mechanism of Action of Tissue-device Interactions
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
Objective: The main objective of this study is to study and understand the underlying biological principles of granulation and fibrotic responses limiting the effectiveness and longevity of BELVR treatment with EBVs, this to investigate the mechanism of action of tissue-device interactions.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Elidgible for EBV treatment
Locations
Other Locations
Netherlands
University Medical Center Groningen
RECRUITING
Groningen
Contact Information
Primary
Dirk-Jan Slebos, MD PhD
d.j.slebos@umcg.nl
+31503616161
Backup
Jorine Hartman, PhD
j.hartman@umcg.nl
Time Frame
Start Date: 2021-03-16
Estimated Completion Date: 2027-03-02
Participants
Target number of participants: 150
Treatments
baseline assessment group
n=150 patiënts for baseline assessment
clinical need for reintervention group
n=20-30 patiënts for re-bronchoscopy
clinical stable controls
n=20 stable treated control patiënts
Related Therapeutic Areas
Sponsors
Leads: University Medical Center Groningen