Long-term Effects of Endobronchial Valve Implantation on Cardiac Function and Skeletal Muscle Function in Patients With Lung Volume Reduction Surgery
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this type of study: clinical trial is to evaluate the effect of bronchial valve implantation on cardiac function and skeletal muscle function in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:evaluate the effect of bronchial valve implantation on cardiac function and skeletal muscle function. Participants will undergo Lung volume reduction surgery with endobronchial valve implantation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: f
View:
• Patients with Chronic Obstructive Pulmonary Disease
• FEV1 ≤ 45% pred and FEV1/FVC\<70%
• TLC\>100% pred and RV\>175% pred
• CAT score≥18
• Emphysema damage\>50%
• Complete interlobar fissure \>95% based on quantitative analysis of CT measurement
• No smoking\>6 months
• Sign the informed consent form
Locations
Other Locations
China
China-Japan Friendship Hospital
RECRUITING
Beijing
Contact Information
Primary
Mingming Deng, MD
isdeng1017@163.com
86 18801336854
Backup
Qin Zhang, MD
zhangqincmu@163.com
86 18990236167
Time Frame
Start Date: 2023-03-27
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 40
Treatments
Experimental: Lung volume reduction surgery group
Related Therapeutic Areas
Sponsors
Leads: China-Japan Friendship Hospital