The Efficacy of Fluticasone Furoate/Vilanterol/Umeclidinium Compared With Vilanterol/Umeclidinium in Reducing Air Trapping and Airway and Blood Cytokine Levels in COPD
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
This study aims to demonstrate the effects of triple therapy (ICS/LABA/LAMA) and dual bronchodilators (LAMA/LABA) on air trapping in the lungs' COPD patients and inflammatory mediators
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 80
Healthy Volunteers: f
View:
• Patients who have met the criteria for COPD GOLD B defined by an exacerbation not more than 1 time in the last year prior to the study enrollment. These patients will be recruited in sequential sequence.
• Patients with COPD GOLD B are previously treated with either LAMA or LAMA/LABA or short-acting bronchodilators
• Patients who are able to provide informed consent.
Locations
Other Locations
Thailand
Division of Respiratory Disease and TB, Siriraj Hospital
RECRUITING
Bangkoknoi
Contact Information
Primary
kittipong maneechotesuwan, MD, PhD.
kittipong.man@mahidol.ac.th
0894996858
Time Frame
Start Date: 2024-10-01
Estimated Completion Date: 2026-12
Participants
Target number of participants: 50
Treatments
Experimental: Treatment 1
Phase 1
Experimental: Treatment 2
Phase 2
Related Therapeutic Areas
Sponsors
Leads: Mahidol University