The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The term Overlap Syndrome (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to study validated outcomes in 3 of these domains: 1) participation in life situations; 2) physical activity; and 3) cardiovascular health. The investigators long-term goal is to develop an exercise strategy tailored to Veterans with OS which will reduce the risk of functional decline through increased PA.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Diagnosis of COPD and OSA, i.e., Overlap Syndrome Diagnosis of Overlap Syndrome (both COPD and OSA), confirmed in CPRS from spirometry or pulmonary function test of FEV1/FVC \<70 for COPD and a polysomnogram or home-based study for OSA.

• Montreal Cognitive Assessment (MoCA) \>20

Locations
United States
Virginia
Salem VA Medical Center, Salem, VA
RECRUITING
Salem
Contact Information
Primary
Tracy A Hicks
Tracy.Hicks2@va.gov
(540) 982-2463
Backup
Donna J Arsura
donna.arsura@va.gov
(540) 982-2463
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 28
Treatments
Experimental: Exercise
The Experimental Design is a randomized trial of Moderate intensity interval training (5-minute intervals at 50% VO2peak 3 times weekly for 12 weeks) in Veterans with COPD and OSA compared with standard of care controls
No_intervention: Usual Care
Participants in the control group will be instructed to maintain their routine activity level for 12 weeks
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov