Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

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Comparison of Exercise Capacity, Muscle Strength and Oxygenation, Arterial Stiffness, Physical Activity and Quality of Life in Individuals With Chronic Obstructive Pulmonary Disease and Impaired Spirometry With Preserved Ratio

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management. Further studies are needed on appropriate approaches for individuals with PRISm to improve respiratory symptoms and prognosis. As research continues to evolve, PRISm needs to be recognized as a critical component of pulmonary assessments and at-risk individuals need to be provided with appropriate treatment and follow-up to prevent progression to COPD. There are no studies in the literature comparing PRISm, respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in COPD and healthy individuals. The aim of this study was to compare respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in PRISm, COPD and healthy subjects.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: t
View:

⁃ PRISm group inclusion criteria;

• Being \>40 years old,

• Being diagnosed with PRISm,

• Volunteering to participate in the study,

• Not having any orthopaedic or neurological problems that may prevent participation in the measurements,

• Co-operation with measurements

• Being \>40 years old,

• Being diagnosed with COPD,

• To be clinically stable,

• Volunteering to participate in the study.

• Being \>40 years old,

• Volunteering to participate in the study,

• No known chronic health problems,

• To be able to co-operate with the measurements.

Locations
Other Locations
Turkey
Hacettepe University
RECRUITING
Ankara
Contact Information
Primary
Ece Kumlu, M.Sc
eekumlu@gmail.com
+90-312-305 2525 ext 178
Time Frame
Start Date: 2025-09-18
Estimated Completion Date: 2026-09
Participants
Target number of participants: 54
Treatments
COPD group
Consisted of 18 individuals over 40 years of age with chronic obstructive pulmonary disease.
PRISm group
Consisted of 18 individuals over 40 years of age with preserved ratio impaired spirometry.
Healthy group
Consisted of 18 healthy individuals over 40 years of age.
Sponsors
Leads: Hacettepe University

This content was sourced from clinicaltrials.gov