Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

Find Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials Near You

Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) Versus Traditional Rapid Shallow Breathing Index (RSBI) for Prediction of Weaning Success From Mechanical Ventilation in COPD Patients

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Mechanically ventilated COPD patients fulfilling standard weaning readiness criteria.

• Invasive mechanical ventilation for more than 24 hours before spontaneous breathing trial.

• Hemodynamically stable without significant vasopressor support.

• Adequate oxygenation with FiO2 ≤ 0.5 and PEEP ≤ 8 cmH2O .

• Preserved mental status and ability to initiate spontaneous breathing.

• Successful tolerance of spontaneous breathing trial conducted on CPAP mode with pressure support ≤ 8 cmH2O.

Locations
Other Locations
Egypt
Sohag University Hospital
RECRUITING
Sohag
Contact Information
Primary
Ahmed Atef Mohamed, MBBCh
ahmed_ateff_post@med.sohag.edu.eg
+201006973892
Time Frame
Start Date: 2026-04-15
Estimated Completion Date: 2027-06
Participants
Target number of participants: 100
Treatments
Mechanically Ventilated COPD Patients
COPD patients receiving invasive mechanical ventilation who fulfill weaning readiness criteria and undergo spontaneous breathing trial with assessment of D-RSBI and conventional RSBI.
Sponsors
Leads: Sohag University

This content was sourced from clinicaltrials.gov