• Are over the age of 19.

• Patients with CRSwNP with or without asthma:

‣ Asthma confirmed with a spirometry and assessment on previous history of asthma (a methacholine challenge test and atopy testing to document positive or negative history of asthma will be performed if there is no clinical record).

⁃ Presence or absence of nasal polyps. This can be based on formal exam at Baseline Visit or historical assessment.

• Patients with CRSsNP with asthma:

‣ These patients will not take the study treatment and they will only complete screening and baseline visits.

• Females of childbearing potential must commit to using an acceptable method of birth control for the duration of the study and they must have a negative urine pregnancy test at each study visit.