Identification of Genetic Factors Implicated in Orofacial Cleft Using Whole Exome Sequencing GENEPIC
Status: Recruiting
Location: See location...
Intervention Type: Genetic
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Despite significant progress made in identification on numerous genes and gene pathways critical for craniofacial development, several approaches, ie mutation screening of specific candidates, association studies and even genome-wide scans have largely failed to reveal the molecular basis of NS human clefting
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Subject with a NSCL/P or CL/P of unknown etiology,
• national health care insurance holders
Locations
Other Locations
France
CHU Amiens Picardie
RECRUITING
Amiens
Contact Information
Primary
Bénédicte DEMEER, MD
demeer.benedicte@chu-amiens.fr
+33 3 22 08 75 81
Time Frame
Start Date: 2016-11-30
Estimated Completion Date: 2027-11-30
Participants
Target number of participants: 30
Treatments
Experimental: Identification of genetic factors
Clinical questionnaire and analysis of genetic data obtained by exome high-throughput sequencing
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire, Amiens