Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery: a Before-and-after Chart Review Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood. Surgical repair is often associated with significant postoperative pain, traditionally managed with morphine, which carries a risk of undesirable side effects. The suprazygomatic maxillary nerve block (SZMNB) has been shown to provide effective analgesia and may reduce the need for opioids. Routine use of SZMNB was introduced at the pediatric surgery unit at Karolinska University Hospital in late 2017. A before-and-after evaluation project based on retrospective chart review was initiated in 2018 but was not completed due to the COVID-19 pandemic. The aim of this project is to investigate whether the introduction of SZMNB has reduced postoperative morphine requirements and opioid-related side effects, and whether this has resulted in shorter hospital stays (earlier discharge) after cleft palate repair.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3 months
Maximum Age: 15
Healthy Volunteers: t
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Locations
Other Locations
Sweden
RECRUITING
Stockholm
Contact Information
Primary
Jacob KarlssonM, MD PhD
jacob.karlsson.1@ki.se
+460812370000
Time Frame
Start Date: 2017-01-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 150
Treatments
Pre-implementation group (2017)
Children who received standard systemic analgesia (intravenous and/or oral opioids, acetaminophen, and NSAIDs) without nerve block.
Post-implementation group (2018)
Children who, in addition to standard systemic analgesia, received a suprazygomatic maxillary nerve block (SZMNB) as part of routine perioperative care.
Related Therapeutic Areas
Sponsors
Leads: Karolinska Institutet

This content was sourced from clinicaltrials.gov