The Role of Diet and the Microbiome in Inducing Somatic Mutations in Colorectal Epithelial Cells and Its Predisposition to Carcinogenesis - A Pilot Study
This study is to learn more about how diet affects the microbiome (bacteria and microorganisms) of the digestive system. Researchers want to learn if this, in turn, has an effect on if and how people then develop colorectal cancer.
• GROUP I: Patients presenting for a screening colonoscopy
‣ GROUP I: Age of 45 and above
⁃ GROUP I: Strict vegetarian diet, determined by using diet history questionnaire 3.0 National Institutes of Health (NIH)
⁃ GROUP I: Non smoker
⁃ GROUP I: Ability to understand and willingness to sign an informed consent form, complete web based dietary assessment and provide stool, colonic mucosa and blood samples
⁃ GROUP II: Patients presenting for a screening colonoscopy
⁃ GROUP II: Age of 45 and above
⁃ GROUP II: Omnivorous diet
⁃ GROUP II: Non smoker
⁃ GROUP II: Ability to understand and willingness to sign an informed consent form, complete web based dietary assessment and provide stool, colonic mucosa and blood sample