Postoperative and Long-term Outcomes of Transanal Tran-section and Single-stapled Anastomosis (TTSS) in Rectal Can-cer Patients: a Multicentric International IDEAL Stage 2b Prospective Parallel Cohort Study
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
The Transanal Transection and Single-Stapled anastomosis (TTSS) technique may be a valid alternative to traditional double-stapled anastomosis for low rectal cancer surgery. This study aims to compare the postoperative and functional outcomes of patients receiving TTSS and traditional double-stapled anastomosis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adult (≥ 18 years old) patients, men and women, diagnosed with rectal cancer scheduled for elective rectal resection with Total Mesorectal Excision (TME) with double-stapled or Transanal Transection and Single-Stapled anastomosis (TTSS) approaches.
• Patients scheduled for open, laparoscopic, or robotic surgery.
• Patients preoperatively indicated for sphincter-saving procedures with or without protective-stoma.
Locations
Other Locations
Italy
IRCCS Humanitas Research Hospital
RECRUITING
Rozzano
Contact Information
Primary
Annalisa Maroli, PhD
colorapp@humanitas.it
02 8224 7776
Backup
Stefano De Zanet, MS
colorapp@humanitas.it
02 8224 4623
Time Frame
Start Date: 2024-03-26
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 472
Treatments
Transanal Transection and Single-Stapled anastomosis (TTSS)
Patients will undergo rectal cancer surgery through low rectal resection with Transanal Transection and Single-Stapled anastomosis (TTSS)
Double-stapled Total Mesorectal Excision (TME)
Patients will undergo rectal cancer surgery through low rectal resection with double-stapled anastomosis Total Mesorectal Excision (TME)
Related Therapeutic Areas
Sponsors
Leads: Istituto Clinico Humanitas