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Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may be at higher risk for colorectal cancer (CRC). The specific objectives of this study are to 1) develop a lifestyle intervention based on evidenced-based diet and lifestyle recommendations (i.e. those proposed by the World Cancer Research Fund (WCRF) and the French National Cancer Institute); 2) evaluate the effect of the intervention on the adherence to the target diet and lifestyle recommendations as well as other subjective health measures, including quality of life; 3) evaluate the effect of the intervention on anthropometrics.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 35
Maximum Age: 74
Healthy Volunteers: f
View:

• Having read the information note and agreeing to participate

• Will and availability to be committed for a full year

• At high risk for CRC but CRC negative

• Affiliated to a health security system

• Having a score on the adherence to the recommendation lower than or equal to 7 out of 9 at baseline.

• Able to read, write and understand French

Locations
Other Locations
France
Centre Léon Bérard
RECRUITING
Lyon
Contact Information
Primary
Inge Huybretchts, PhD
huybrechtsi@iarc.who.int
+33695925958
Backup
Genevieve Nicolas, MSc
nicolasg@iarc.who.int
Time Frame
Start Date: 2026-01-26
Estimated Completion Date: 2028-02-15
Participants
Target number of participants: 800
Treatments
No_intervention: Control
Colorectal cancer free participants receive the 'usual care' following a positive FIT test and diagnostic colonoscopy
Active_comparator: Intervention
Colorectal cancer free participants receive evidence-based diet and lifestyle advice in addition to the 'usual care' following a positive FIT test and diagnostic colonoscopy
Related Therapeutic Areas
Sponsors
Collaborators: University of Bordeaux, Hôpital Edouard Herriot, International Agency for Research on Cancer
Leads: Centre Leon Berard

This content was sourced from clinicaltrials.gov