Identification of New Non-invasive, Predictive, and Diagnostic Biomarkers for Colorectal Cancer
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The study in question is an observational study that aims to identify new non-invasive biomarkers present in the serum of patients with CRC and, subsequently, to create a score capable of predicting the development of CRC. It is an observational study with 3 enrollment arms: Arm 1: Patients undergoing surgery at the U.O.C. of Surgery, with a CRC diagnosis; Arm 2: Subjects with a negative result from the endoscopic examination; Arm 3: Subjects in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• AIM 1: Patients undergoing surgery at the U.O.C. of Surgery, with a diagnosis of CRC.
• AIM 2: Subjects without colon disease.
• AIM 3: Subjects with adenoma and high-grade dysplasia.
Locations
Other Locations
Italy
Biobank Core Facility
RECRUITING
Castellana Grotte
Contact Information
Primary
Pasqua Letizia Pesole, Biologist
letizia.pesole@irccsdebellis.it
+390804994365
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2027-12-01
Participants
Target number of participants: 60
Treatments
Patients undergoing surgery at the Department of Surgery, with a diagnosis of CRC;
Patients undergoing surgery at the Department of Surgery, with a diagnosis of CRC;
Subjects with a negative endoscopic examination result.
Subjects who attend our Institution's Department of Digestive Endoscopy for a colonoscopy performed for diagnostic purposes, with a negative endoscopic examination result.
Subjects with a diagnosis of adenoma with high-grade dysplasia, a condition considered pre-cancerous
Subjects who attend our Institution's Department of Digestive Endoscopy for a colonoscopy performed for diagnostic purposes, or patients undergoing a surgical procedure at the Department of Surgery, in whom the presence of an adenoma with high-grade dysplasia is found, a condition considered pre-cancerous.
Related Therapeutic Areas
Sponsors
Collaborators: University of Bari Aldo Moro
Leads: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis