Determining the Success of a Urine Metabolite Point-of-care Colorectal Cancer Early Diagnosis Test in Africa
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The purpose of this study is to find out whether a urine test can detect colorectal cancer (CRC) and precancerous polyps in participants living in Ghana, Tanzania, and South Africa.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patient presents with one of the following:
‣ Patients with symptoms of CRC (such as rectal bleeding for a week) -OR-
⁃ Patients who present for a screening colonoscopy -OR-
⁃ Has received one of the following within 3 weeks of the planned urine collection
• Patients with a pathologic diagnosis of CRC either by colonoscopy or resection specimens -OR-
∙ Patients with colonoscopy demonstrating adenomatous polyps -OR-
∙ Patients with colonoscopy demonstrating no colon or premalignant or malignant pathology
• Age ≥ 18
• Willingness to participate in the study
Locations
United States
New York
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING
New York
Other Locations
Ghana
Korle Bu Teaching Hospital (Data Collection Only)
NOT_YET_RECRUITING
Accra
South Africa
Wits Donald Gordon Medical Centre (Data Collection Only)
NOT_YET_RECRUITING
Johannesburg
United Republic of Tanzania
Kilimanjaro Christian Medical Centre (Data Collection Only)
NOT_YET_RECRUITING
Moshi
Contact Information
Primary
Peter Kingham, MD
kinghamP@mskcc.org
212-639-5260
Backup
Alexia Iasonos, PhD
iasonosa@mskcc.org
646-227-3557
Time Frame
Start Date: 2026-06-11
Estimated Completion Date: 2028-06-11
Participants
Target number of participants: 210
Treatments
Participants with Colorectal Cancer/CRC
Participants will either have symptoms of colorectal cancer/CRC, presented for a screening colonoscopy, or one of the following: pathologic diagnosis of CRC, colonoscopy demonstrating adenomatous polyps, or colonoscopy demonstrating no colon or premalignant or malignant pathology
Related Therapeutic Areas
Sponsors
Leads: Memorial Sloan Kettering Cancer Center