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Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers

Status: Recruiting
Location: See all (16) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with suspected or proven sigmoid colon adenocarcinoma, eligible for curative treatment whose MRI can be reviewed prior to surgery and has no decision regarding radical treatment are eligible. Patient are randomised to the control arm which the standard care of preoperative CT imaging and subsequent discussion by the Multidisciplinary Team or the interventional arm which has the additional use of MRI imaging and subsequent discussion by the Multidisciplinary Team. Patients are followed up at 1 and 3 years together with QoL questionnaires.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:

• Have a suspected or proven sigmoid colon adenocarcinoma

• Is eligible for curative treatment

• Has no irresectable metastatic disease

• MRI can be reviewed by an MDT prior to surgery

• Has no decision regarding radical treatment

• Have provided written informed consent to participate in the study

• Be aged 16 years or over

Locations
Other Locations
United Kingdom
Chesterfield Royal
RECRUITING
Chesterfield
Leighton Hospital
RECRUITING
Crewe
North Manchester General Hospital
RECRUITING
Crumpsall
Harrogate District Hospital
RECRUITING
Harrogate
Hinchingbrooke Hospital
RECRUITING
Huntingdon
Maidstone Hospital
RECRUITING
Maidstone
Queen Elizabeth the Queen Mother Hospital
RECRUITING
Margate
St Mark's Hospital
RECRUITING
Middlesex
Queen Alexandra Hospital
RECRUITING
Portsmouth
Salisbury District Hospital
RECRUITING
Salisbury
University Hospital of North Tees
RECRUITING
Stockton-on-tees
Royal Marsden Hospital
RECRUITING
Sutton
Musgrove Park Hospital
RECRUITING
Taunton
Croydon University Hospital
RECRUITING
Thornton Heath
University Hospital of South Manchester & Manchester Royal Infirmary
RECRUITING
Wythenshawe
Yeovil District Hospital
ACTIVE_NOT_RECRUITING
Yeovil
Contact Information
Primary
Caroline Martin
c.martin1@imperial.ac.uk
+44 (0) 7749 655 817
Backup
Syvella Ellis
giclinicaltrials@imperial.ac.uk
+44 (0) 7732 315 234
Time Frame
Start Date: 2014-08
Estimated Completion Date: 2031-12
Participants
Target number of participants: 244
Treatments
No_intervention: Preoperative CT scan
CT-imaging of chest and abdomen / pelvis before surgery (standard treatment)
Experimental: Preoperative MRI scan
Standard treatment plus an additional MRI scan before surgery
No_intervention: Observational
Observational only
Authors
Gina Brown
Related Therapeutic Areas
Sponsors
Collaborators: Pelican Cancer Foundation
Leads: Imperial College London

This content was sourced from clinicaltrials.gov

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