The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics in Adults Undergoing Minimally Invasive Abdominopelvic Surgery: An Intraoperative Observational Study

Status: Recruiting
Location: See location...
Intervention Type: Device, Other
Study Type: Observational
SUMMARY

During certain bowel surgeries for cancer (colorectal surgery), individuals frequently have to be placed in a head-down position to enable surgeons have optimal access to the cancer site. This position usually also involves bending the hips and knees while supporting the legs in stirrups. However, lying in this position for long periods of time can lower the flow of blood to the legs, which can potentially cause injury. This rare but severe consequence is called Well-Leg Compartment Syndrome (WLCS). If WLCS is not diagnosed quickly, it can lead to other difficult complications and a significant delay in recovery. Unfortunately, because the individual is under anaesthesia, diagnosis is delayed in many cases. There is very little information in the medical literature about how this damage to the legs progresses over the course of the surgery. To better understand how WLCS, how well blood vessels work during surgery will be assessed. The flow of blood and oxygen in the calf muscle will be assessed in 25 individuals placed in a head-down position during colorectal surgery. Likewise, blood samples will be obtained in order to measure the biological markers that may contribute to the development of WLCS.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults scheduled to undergo colorectal surgery in the HDTL position

Locations
Other Locations
United Kingdom
Queen Alexandra Hospital, Portsmouth Hospitals University NHS Trust
RECRUITING
Portsmouth
Contact Information
Primary
Maria C Perissiou, PhD
maria.perissiou@port.ac.uk
+44 7762860432
Backup
Chukwuemeka C Uzoma, MBBS
chukwuemeka.uzoma@port.ac.uk
+44 7466733040
Time Frame
Start Date: 2024-07-22
Estimated Completion Date: 2025-12
Participants
Target number of participants: 25
Treatments
Colorectal surgery
Individuals scheduled for colorectal surgery in the HDTL position
Related Therapeutic Areas
Sponsors
Collaborators: Portsmouth Hospitals NHS Trust
Leads: University of Portsmouth

This content was sourced from clinicaltrials.gov