A Randomized, Double-blind, Placebo-controlled Study to Investigate the Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome
The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how cannabinoids produce stabilized improvement in CRPS-related pain and comorbidities. The trial consisted of a pre-treatment screening period, six-week treatment period and a two-week follow-up.
• Provision of signed and dated informed consent form.
• Are between 21-75 years old
• Ability to communicate in English
• Volunteers with no previous medical history (e.g., cardiac or pulmonary disease)
• Are not currently using any type of cannabis, including hemp or CBD
• Currently 30 days cannabis free
• Participants with ongoing CRPS \[Type 1 or Type 2)\] for at least 3 months prior to participation (medical record confirmed)
• Agrees not to use cannabis, including hemp or CBD, outside of the study during participation in the study
• Agrees not to use opioids or barbiturates during participation in the study