Rehabilitation of Adult Patients With Post Concussion Syndrome

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome (PCS). The project investigates the phenomenon Post Concussion Syndrome in four dimensions with a focus on both patient perspectives of PCS, an interventional physical program, a neurobiological basis for PCS through Magnetic Resonance Imaging (MRI) and finally through a 360-degree evaluation of the entire project involving patients and scientists in a reflective process.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: t
View:

• Post concussion syndrome (PCS) diagnose according to WHO ICD-10 classification and documented by written statement from physician veritying a mild traumatic brain injury

• Longer lasting symptoms for at least 4 weeks after initial trauma

• If allocated to add-on exercise protocol participant must feel able to prioritize the intervention structure

• Communication language must be Danish

Locations
Other Locations
Denmark
University College Copenhagen
RECRUITING
Copenhagen
Contact Information
Primary
Henrik BW Larsson, Professor
henrik.bo.wiberg.larsson@regionh.dk
(+45) 24824294
Backup
Mette K Zebis, PhD
mzeb@kp.dk
(+45) 30291943
Time Frame
Start Date: 2023-02-01
Estimated Completion Date: 2026-04
Participants
Target number of participants: 70
Treatments
Experimental: Aerobe graded physical exercise intervention and usual care
Physical exercise program. The experimental programme is an add-on to usual care and consists of an aerobe graded exercise program performed twice a week for 12 weeks. Usual care includes all public treatments that each patient is assigned to at entry to REPCon. The provision of officially available treatments follow the Danish Health Care Act.
Placebo_comparator: Usual care
No physical exercise program in a patient control group with PCS. This group continues with usual care, but all clinical test, interviews and MRI protocol are the same.
Related Therapeutic Areas
Sponsors
Leads: Rigshospitalet, Denmark
Collaborators: University College Copenhagen

This content was sourced from clinicaltrials.gov