The Effects of Chiropractic Manual Adjustments on Nervous System Function in Individuals with Post-concussion Syndrome: a Proof of Concept Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome. This study will aim to recruit 10 individuals to receive 6 weeks of chiropractic care with 3 assessment periods. The participants will undergo a baseline assessment, mid-trial assessment, and post-trial assessment. The participants will wear an electroencephalography (EEG) cap for a neural assessment during an event related potential. They will wear electrical diodes to measure electrocardiography (ECG), impedance cardiography (ICG), and electrodermal activity (EDA) throughout the study and during an orthostatic challenge. Additional sensors will be placed on the participant to measure interlimb symmetry patterns during gait while walking on a treadmill.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 or older

• Diagnosed by a physician with post-concussion syndrome OR self-identifies as having a concussion based on responses to the HELPS screening tool

• Has at least 3 of the following chronic symptoms at least 3 months since concussion: headache; dizziness; insomnia; fatigue; concentration difficulty; memory difficulty; intolerance to stress, emotions, and alcohol; irritability

• Able to understand and communicate in English

• Able to make informed decisions without assistance

• Can wear an EEG net for 40 minutes

• Can sit quietly for at least 15 minutes

• Capable of walking on a treadmill at a comfortable pace for 10 minutes consecutively

• Capable of moving from a supine to standing to supine position quickly and safely

• Able to wear multiple electrodes placed on chest, back, and fingertips

• Able to wear multiple sensors placed on head, back, pelvis, hands, arms, and legs

• Has not had a chiropractic adjustment within the last one month

• Has not received any other interventions within the past one month such as osteopathic spinal manipulation, physical therapy rehabilitation or manipulation, massage, body movement therapies, or acupuncture

Locations
United States
Georgia
Dr. Sid E. Williams Center for Chiropractic Research
RECRUITING
Marietta
Contact Information
Primary
Daekiara Smith-Ireland, MPH
research.studies@life.edu
7704262639
Time Frame
Start Date: 2024-01-27
Estimated Completion Date: 2026-07-31
Participants
Target number of participants: 10
Treatments
Experimental: Post-concussion syndrome participants
Post-concussion syndrome participants will all receive manual chiropractic adjustment interventions.
Related Therapeutic Areas
Sponsors
Leads: Life University

This content was sourced from clinicaltrials.gov