HIT HEADS 3.0: Head Injury Treatment: A Randomized, Placebo-controlled, Double-blinded, Therapeutic Clinical Trial of Branched Chain Amino Acids (BCAAs) in the Treatment of Concussion
This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAAs) in the treatment of concussion. The aim of the study is to determine whether administration of high-dose BCAAs compared to placebo promotes concussion recovery.
• Males and females,11 - 23 years of age.
• Weigh at least 40kg.
• Meeting concussion criteria for the American Congress of Rehabilitative Medicine.
• a. One or more clinical signs or two or more acute symptoms with at least one VVE abnormality.
• Present within 4 days of injury.
• Post-menarchal females must have a negative urine pregnancy test.
• Informed consent by the participant, or for participants \<18 years old both informed consent by a parent/guardian and child assent.