Congenital Heart Disease (CHD) Clinical Trials

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Psychological Trauma, Post-Traumatic Stress Disorder, and Resilience in Adults With Congenital Heart Disease

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Observational
SUMMARY

The purpose of this study, entitled Psychological trauma, post-traumatic stress disorder, and resilience in adults with congenital heart disease in a large population sample, is to evaluate for exposures during a lifetime with congenital heart disease that may be associated with higher likelihood of developing PTSD. Primary aim: \- Identify individual patient characteristics (medical, psychosocial, socioeconomic, etc.) that are associated with a diagnosis of PTSD. Secondary aims: * Calculate the prevalence of those meeting PTSD criteria in the ACHD population using the gold standard diagnostic clinician interview, while using the same data to validate a PTSD screening self-report survey in the ACHD population. * Determine the role of resilience in ACHD patients using a validated screening survey to assess its protective role toward PTSD. Hypotheses: * There are certain exposures (e.g. post-surgical pain, ICU delirium, bullying due to CHD) that are associated with a higher incidence and odds of meeting PTSD criteria. * Gold standard diagnostic interviews will most accurately estimate the prevalence of PTSD in ACHD which has been overestimated on prior screening-based studies, although the scope of the problem is still great. * Patients with a higher resilience score will show an association with a lower risk of PTSD.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Congenital heart disease diagnosis, age \>= 18 years

• Enrolled in CHI registry

• English proficiency for survey completion

• Access to an internet connection. Can be via computer or handheld device.

Locations
United States
Washington, D.c.
Children's National Medical Center
NOT_YET_RECRUITING
Washington D.c.
New Hampshire
Dartmouth Hitchcock Medical Center
RECRUITING
Lebanon
Ohio
Nationwide Children's Hospital
NOT_YET_RECRUITING
Columbus
Contact Information
Primary
David J Harrison, MD
david.j.harrison@hitchcock.org
603-650-5724
Backup
Jamie Jackson, PhD
jamie.jackson2@nationwidechildrens.org
Time Frame
Start Date: 2025-09-01
Estimated Completion Date: 2026-08
Participants
Target number of participants: 1000
Treatments
Overall cohort
Adults age \>= 18-years with a diagnosis of congenital heart disease.~Congenital heart disease will be defined by previously published classification including those listed in the American Heart Association/ American College of Cardiology guidelines for the care of adults with congenital heart disease.
Sponsors
Collaborators: Adult Congenital Heart Association
Leads: Dartmouth-Hitchcock Medical Center

This content was sourced from clinicaltrials.gov