A Rational Approach to the Identification of New Treatment Options to Prevent Congenital Syphilis: Phase 1 Study of the Pharmacokinetics of Amoxicillin in Pregnancy
Status: Completed
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
The study design is a prospective phase I pharmacokinetic study focused on dosing of 500 mg oral amoxicillin administration in pregnant women in the 2nd and 3rd trimester.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 16
Maximum Age: 50
Healthy Volunteers: f
View:
• Pregnant, engaged in prenatal care with a medical provider (at least one visit)
• Estimated gestational age 24-34 weeks
• Able to provide informed consent
• English speaking
Locations
United States
Alabama
UAB
Birmingham
Time Frame
Start Date: 2023-08-29
Completion Date: 2025-06-30
Participants
Target number of participants: 13
Treatments
Experimental: Amox 500 mg
Amoxicillin 500 mg PO
Related Therapeutic Areas
Sponsors
Leads: University of Alabama at Birmingham