Impact of Stenosis and Plaque Features in Coronary CT Angiography, Physiologic Assessment and Pharmacotherapy on the Clinical Outcomes After Invasive Coronary Angiography

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The investigators aim to investigate the prognostic implication of stenosis and plaque features on coronary CT angiography (CCTA), physiologic assessment, and pharmacotherapy after invasive coronary angiography.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
View:

• Age ≥ 20 years

• Patients who undergo CCTA within 90 days before FFR measurement by clinical needs

• Patients with a vessel determined to defer revascularization after FFR measurement.

• Age ≥ 20 years

• Patients who undergo CCTA within 90 days before FFR measurement by clinical needs

• Patients with a vessel that undergo stent implantation and FFR measurement both before and after revascularization (pre-PCI FFR and post-PCI FFR).

⁃ Patients with multiple vessels that meet inclusion criteria of the deferral of PCI group and PCI group will be assigned to the PCI group.

Locations
Other Locations
Republic of Korea
Seoul National University Hospital
RECRUITING
Seoul
Contact Information
Primary
Bon-Kwon Koo, MD, PhD
bkkoo@snu.ac.kr
+82-1033561869
Backup
Seokhun Yang, MD
newturnz7@gmail.com
+82-1025953470
Time Frame
Start Date: 2020-08-12
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 992
Treatments
Deferral of PCI group
Patients with a vessel determined to defer revascularization after FFR measurement who undergo CCTA within 90 days before FFR measurement will be included.
PCI group
Patients with a vessel that undergo stent implantation and FFR measurement both before and after revascularization (pre-PCI FFR and post-PCI FFR) with available coronary CT angiography within 90 days before FFR measurement will be included.
Related Therapeutic Areas
Sponsors
Collaborators: Seoul National University Bundang Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University, Ulsan Hospital, Keimyung University Dongsan Medical Center, Dong-A University Hospital, Dong-A ST Co., Ltd., Incheon St.Mary's Hospital, Tsuchiura Kyodo General Hospital, Gachon University Gil Medical Center, Sejong General Hospital, Inje University, Chosun University Hospital, Wonju Severance Christian Hospital
Leads: Seoul National University Hospital

This content was sourced from clinicaltrials.gov