Prognostic Impact of Lesion-specific Hemodynamic Index and Disease Characteristics in Patients With Coronary Artery Disease Assessed by Fractional Flow Reserve
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The investigators aim to investigate the additive prognostic value of lesion-specific hemodynamic index such as ΔFFR, non-hyperemic pressure ratio such as RFR, over % diameter stenosis and FFR according to treatment strategy, and to find the prognostic implications of post-PCI FFR after adjustment of various clinical and disease characteristics, and to construct a comprehensive risk prediction model for post-PCI outcomes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:
• Age ≥20 years
• All comers who underwent successful FFR measurement and pullback tracing
Locations
Other Locations
Republic of Korea
Seoul National University Hospital
RECRUITING
Seoul
Contact Information
Primary
Bon-Kwon Koo, MD, PhD
bkkoo@snu.ac.kr
+82-2-2072-2062
Backup
Seokhun Yang, MD
newturnz7@gmail.com
+82-2-2072-2062
Time Frame
Start Date: 2021-08-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 2429
Treatments
Deferral of PCI group
Patients who undergo successful FFR pullback tracing and have a vessel determined to defer revascularization after FFR measurement will be included.
PCI group
Patients who undergo successful FFR pullback tracing and have a vessel that undergo stent implantation and FFR measurement both before and after revascularization (pre-PCI FFR and post-PCI FFR) will be included.
Related Therapeutic Areas
Sponsors
Collaborators: Seoul National University Bundang Hospital, Dong-A University Hospital, Tsuchiura Kyodo General Hospital, Gyeongsang National University Hospital, KangWon National University Hospital, Inje University, Severance Hospital, Ulsan University Hospital, Wonju Severance Christian Hospital, Keimyung University Dongsan Medical Center
Leads: Seoul National University Hospital