Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study sought to evaluate whether ezetimibe combination to high-intensity statin therapy will have more prominent beneficial effect compared to high-intensity statin monotherapy in patients who underwent coronary revascularization with newer generation drug-eluting stent (DES) implantation. Furthermore, the optimal OCT-based optimal expansion criteria as well as the efficacy and safety of newer generation will be investigated.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
View:
• Age 19-85 years
• Patients who underwent coronary revascularization with newer generation DES implantation
Locations
Other Locations
Republic of Korea
Yonsei University Health System, Severance Hospital
RECRUITING
Seoul
Contact Information
Primary
Byeong-Keuk Kim
kimbk@yuhs.ac
82-2228-8460
Time Frame
Start Date: 2023-04-07
Estimated Completion Date: 2027-12
Participants
Target number of participants: 4310
Treatments
Experimental: Combination therapy group
Ezetimibe/high-intensity statin combination therapy
Active_comparator: Statin monotherapy group
High-intensity statin monotherapy
Related Therapeutic Areas
Sponsors
Leads: Yonsei University