CT Myocardial Perfusion Imaging to Guide the Diagnosis and Treatment of Patients With Stable Coronary Artery Disease: a Randomized Controlled Study (POTENTIAL)
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Procedure, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The overall goal of this project is to compare the non-revascularization rate of coronary angiography in patients with stable coronary artery disease (CAD) within 90 days after CT myocardial perfusion imaging (CT-MPI) or Single-Photon Emission Computed Tomography myocardial perfusion imaging (SPECT-MPI), and 1-year major adverse cardiovascular events (MACE).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age ≥18 years
• Patients with stable chest pain who have undergone coronary CT angiography and have 50-90% stenosis in at least one vessel \> 2mm in diameter
• Able to provide signed informed consent
Locations
Other Locations
China
Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences
RECRUITING
Beijing
The Second Norman Bethune Hospital of Jilin University
ACTIVE_NOT_RECRUITING
Changchun
Fuwai Central China Cardiovascular Hospital
ACTIVE_NOT_RECRUITING
Zhengzhou
The First Affiliated Hosptial of Zhengzhou University
ACTIVE_NOT_RECRUITING
Zhengzhou
Contact Information
Primary
Yang Gao, M.D
gaoyang226@126.com
86-10-88322656
Time Frame
Start Date: 2023-09-30
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 660
Treatments
Experimental: CT-MPI guided without myocardial ischemia
There was no evidence of myocardial ischemia in patients with coronary heart disease by CT-MPI
Experimental: CT-MPI guided with myocardial ischemia
There was positive evidence of myocardial ischemia in patients with coronary heart disease by CT-MPI
Active_comparator: SPECT-MPI guided without myocardial ischemia
There was no evidence of myocardial ischemia in patients with coronary heart disease by SPECT-MPI
Active_comparator: SPECT-MPI guided with myocardial ischemia
There was positive evidence of myocardial ischemia in patients with coronary heart disease by SPECT-MPI
Related Therapeutic Areas
Sponsors
Leads: Chinese Academy of Medical Sciences, Fuwai Hospital