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Correlation of Fractional Flow Reserve Computed Tomography (FFR CT) Findings With Invasive FFR in Coronary Artery Disease (CAD) in a Multi-ethnic Cohort- a Retrospective Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This study aims to examine the correlation between Fractional Flow Reserve (FFR) FFR Computed Tomography (CT) and invasive FFR in a real-world setting using retrospective analysis of existing data, providing practical insights directly applicable to patient care. By confirming or examining the accuracy of FFR CT in a clinical setting, our analysis could support its broader adoption as a routine non-invasive diagnostic tool potentially (a) reducing the need for invasive testing (b) minimising associated risks, and(c) lowering healthcare costs and provide fresh insights into non-invasive coronary diagnostics. Our findings will also help understand the relevance of these tests across different ethnic groups and the population we serve.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• •≥18 years

‣ Stable •patients with suspected CAD

⁃ Patients who underwent CTCA, FFR CT and had an invasive FFR.

⁃ CTCA images of high-quality for analysis, with clear visualisation of coronary arteries and minimal artifacts.

Locations
Other Locations
United Kingdom
Sandwell and West Birmingham NHS Trust
RECRUITING
Birmingham
Contact Information
Primary
Vinoda Sharma, FRCP FESC FRCPE
vinodasharma@nhs.net
0044 1215075841
Time Frame
Start Date: 2026-05-01
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 500
Related Therapeutic Areas
Sponsors
Collaborators: Aston University
Leads: Sandwell & West Birmingham Hospitals NHS Trust

This content was sourced from clinicaltrials.gov