Use of Shock Wave Therapy for Neo-Vascularisation in Non-critical Coronary Artery Disease: Validation by Quantitative Cardiac MRI Perfusion
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a randomised controlled trial aimed to demonstrate the effect of cardiac extracorporeal shock wave therapy (CSWT) on the angiogenesis effect of myocardium by determining myocardial perfusion and left ventricular function in patients with coronary artery disease (CAD) when measured by cardiac MRI before and after the treatment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Patients with symptoms of coronary artery disease
• Patients without obstructive coronary artery disease
• with LVEF not \< 40%.
Locations
Other Locations
Hong Kong Special Administrative Region
HKU Li Ka Shing Faculty of Medicine
RECRUITING
Hong Kong
Contact Information
Primary
Ming-Yen NG, BMBS
myng2@hku.hk
22554524
Time Frame
Start Date: 2020-09-01
Estimated Completion Date: 2026-01-01
Participants
Target number of participants: 100
Treatments
Experimental: CSWT
Cardiac patients who have progressively increasing coronary plaque burden that is not yet at a critical stage of the CAD process and are randomised to the group receiving extracorporeal shock wave therapy. Cardiac MRI scans will be done before the treatment and 6 months after the end of CSWT.
No_intervention: No intervention
The other half of similar cardiac patients who do not receive CSWT. Optimised medical therapy will be given to patients in this group. Cardiac MRI scans will be done twice.
Related Therapeutic Areas
Sponsors
Leads: The University of Hong Kong