Serological and PCR Testing for SARS-CoV-2. A Prospective Study Assessing Infection, Immunity, and Asymptomatic Carriage of COVID-19

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Richmond Research Institute (RRI) is applying existing and new COVID-19 PCR and antibody tests to help develop methodologies which provide fast and accurate results. Infection with coronavirus (SARS-CoV-2) is currently a worldwide pandemic and reliable testing for COVID-19 is crucial to understand who is infected and therefore a risk to others by spreading the infection. RRI are currently carrying out the following tests: A. Using a membrane-based immunoassay to detect IgG and IgM antibodies to SARS-CoV-2 in whole blood, serum or plasma specimens helps to assess whether an individual has previously had the virus and is potentially immune B. Polymerase Chain Reaction (PCR) testing using an established method to check for active SARS-CoV-2 infections. C. Quantification of anti-SARS-CoV-2 IgG and IgM antibodies in whole blood samples. The above tests are being used by RRI to follow infections (PCR) and immunity (IgG) in their workforce, as well as their families (including children) and visitors to their site. Collecting this data allows the gathering of epidemiological data on SARS-CoV-2 including incidence, prevalence, information on asymptomatic carriers and efficacy of vaccination. Furthermore, identifying individuals that are infected with SARS-CoV-2 has great potential to improve health outcomes by allowing infected individuals to seek the correct medical treatment as well as self-isolate and reduce transmission.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 70
Healthy Volunteers: t
View:

• Male or female aged 5 to 70 years.

• An understanding, ability, and willingness to fully comply with the project procedures and restrictions.

Locations
Other Locations
United Kingdom
Richmond Pharmacology Ltd. 1a Newcomen St, London Bridge
RECRUITING
London
Contact Information
Primary
Jorg Taubel, MD
j.taubel@richmondpharmacology.com
+44(0)2070425800
Backup
Ulrike Lorch, MD
u.lorch@richmondpharmacology.com
+44(0)2038482005
Time Frame
Start Date: 2020-03-16
Estimated Completion Date: 2026-01
Participants
Target number of participants: 2500
Treatments
Trial Participants
Male and female participants aged 5-70 years
Related Therapeutic Areas
Sponsors
Collaborators: Richmond Pharmacology Limited
Leads: Richmond Research Institute

This content was sourced from clinicaltrials.gov